Why the study?
Does dabigatran reduce ischemic stroke, intracranial hemorrhage, and death compared to warfarin in patients with atrial fibrillation and a risk of stroke?
Population
439 patients with atrial fibrillation and a risk of stroke
Comparison
Dabigatran (110 mg or 150 mg) vs Warfarin
Design
Cohort
Authors
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Dabigatran was associated with lower ischemic stroke and mortality than warfarin in AF; hypothesis-generating and should not yet change practice.
Does dabigatran reduce ischemic stroke, intracranial hemorrhage, and death compared to warfarin in patients with atrial fibrillation and a risk of stroke?
Dabigatran was associated with lower rates of ischemic stroke and all-cause mortality compared to warfarin in patients with atrial fibrillation.
Aslan et al. (2014) studied this question.
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