Experimental study reveals aggravated cortical metabolic disruption from hypercapnia during stroke in baboons, suggesting an intracerebral steal phenomenon.
The cortical circulation of the baboon has been studied during ischaemia produced by middle cerebral occlusion. Evidence of reactive hyperaemia did not occur in hypercapnia. Metabolic studies as a whole present evidence of increased interference with gaseous metabolism during hypercarbic occlusion, despite raised venous pO(2) during hypercarbia. The significance of these findings is discussed.
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Symon et al. (1971) studied this question.
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