Association between Albumin Creatinine Ratio and e-GFR in Type 2 Diabetes Mellitus Patients in Oredo Local Government Area, Benin City, South-South Nigeria

Background: Diabetes mellitus is the commonest endocrine disease in Nigeria. Nephropathy is one of the complications of type 2 diabetes mellitus that could lead to end stage renal disease. Persistent microalbuminuria is a predictor of high risk of developing diabetic nephropathy. Early detection of kidney disease and intervention will prevent progression to end stage renal disease. Objective: To determine the association between albumin creatinine ratio and eGFR in type 2 diabetic patients, their usefulness as early predictors of diabetic nephropathy and progression of disease. Materials and Methods: This was a cross sectional study conducted in the State Specialist Hospital, Benin City, Edo State, Nigeria. Forty six type 2 diabetes mellitus patients, both male and female within the age range of 30 -85 years were recruited for the study, after meeting the inclusion criteria. Twenty age and gender matched healthy subjects were selected as controls. Fasting plasma glucose, glycated haemoglobin, C-Reactive protein, serum creatinine were assayed. Urine albumin was estimated and albumin creatinine ratio determined, eGFR was