Population
Several different cell lines
Design
Preclinical
Follow-up
24 h after infection
Authors
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Adds mechanistic insight into EV71 pathogenesis; leaves open clinical relevance and therapeutic targeting in humans.
EV71 and its 2A protease induce apoptosis in infected cells, adding to the understanding of viral pathogenesis.
Kuo et al. (2002) studied this question.
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