Why the study?
Does oral contraceptive use increase the risk of nonfatal myocardial infarction in young women?
Population
107 women younger than 46 years discharged with acute myocardial infarction and 59 control women.
Comparison
Oral contraceptives vs Nonusers of oral contraceptives
Design
Case-control
Authors
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May warrant caution prescribing oral contraceptives to young women; leaves open risk magnitude with modern low-dose formulations.
Does oral contraceptive use increase the risk of nonfatal myocardial infarction in young women?
Oral contraceptive use in young women, particularly those who smoke and are older than 37 years, is associated with a significantly increased risk of nonfatal myocardial infarction.
Hershel Jick (1978) studied this question.
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