Why the study?
Does HIV infection increase aortic stiffness compared to uninfected controls?
Does HIV infection increase aortic stiffness compared to uninfected controls?
While baseline aortic stiffness did not differ between HIV-infected individuals and controls, past severe immunodeficiency (nadir CD4 <200) was independently associated with accelerated vascular aging, supporting early antiretroviral initiation.
No takes yet. Share an insight, caveat, or question.
Nadir CD4 count was associated with faster cf-PWV progression in HIV; leaves open whether early ART slows vascular aging.
Maia-Leite et al. (2016) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: