Why the study?
cLBBB is associated with poor outcomes in HF but has minimal effects on CV mortality in healthy adults; risk stratification under conventional versus new strict criteria in patients with normal EF was needed.
Does complete left bundle branch block increase the risk of cardiovascular mortality and heart failure in patients with normal left ventricular ejection fraction?
Population
137 patients with cLBBB and LVEF > 50% plus age- and sex-matched controls
Comparison
cLBBB (conventional or strict) vs controls without intraventricular conduction abnormalities
Design
Matched cohort study
Follow-up
Median 4.3 years
Authors
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May warrant closer HF surveillance even with preserved EF; leaves open whether early intervention can modify associated risk.
Does complete left bundle branch block increase the risk of cardiovascular mortality and heart failure in patients with normal left ventricular ejection fraction?
In patients with normal ejection fraction, the presence of complete left bundle branch block (whether strict or conventional) is associated with a significantly increased risk of cardiovascular mortality, heart failure admission, and ejection fraction reduction.
Huang et al. (2020) studied this question.
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