Key result
In patients with normal ejection fraction, left bundle branch block with an abnormal stress echocardiogram was associated with an increased risk of all-cause mortality (HR 2.4; 95% CI 1.4-4.2; P=0.002).
Why the study?
What is the prognostic value of stress echocardiography in patients with complete bundle branch block and normal LVEF?
Population
7,214 patients referred for stress echocardiography with normal left ventricular ejection fraction, mean age…
Comparison
Stress echocardiography in patients with… vs Patients without bundle branch block, and…
Design
Cohort
Follow-up
mean 9 ± 4 years
Authors
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May refine prognosis in LBBB with normal LVEF; leaves open whether results should guide interventions or trials.
Cohort (n=7,214)
What is the prognostic value of stress echocardiography in patients with complete bundle branch block and normal LVEF?
Hazard Ratio: 2.4 (95% CI 1.4–4.2)
p-value: p=0.002
A normal stress echocardiogram in patients with LBBB and normal LVEF indicates a benign prognosis, whereas an abnormal stress echocardiogram is associated with a significantly increased risk of mortality.
Supariwala et al. (2014) conducted a cohort in Complete bundle branch block with normal left ventricular ejection fraction (n=7,214). Left bundle branch block with abnormal stress echocardiography vs. Normal stress echocardiography was evaluated on All-cause mortality (HR 2.4, 95% CI 1.4-4.2, p=0.002). In patients with normal ejection fraction, left bundle branch block with an abnormal stress echocardiogram was associated with an increased risk of all-cause mortality (HR 2.4; 95% CI 1.4-4.2; P=0.002).