Why the study?
Evaluation for MI in EDs is resource-intensive, and it was unknown whether a 0/1-hour hs-cTnI accelerated protocol reduces health care resource utilization compared with traditional 0/3-hour standard care.
Does a 0/1-hour hs-cTnI accelerated protocol reduce health care resource utilization compared with a traditional 0/3-hour standard care protocol in ED patients with suspected MI?
Population
32 608 consecutive ED patients evaluated for suspected MI across 9 EDs in Michigan
Comparison
0/1-hour hs-cTnI accelerated protocol vs traditional 0/3-hour standard care protocol
Design
Prespecified secondary analysis of a stepped-wedge randomized clinical implementation trial
Follow-up
30 days
Authors
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Supports 0/1-hour hs-cTnI adoption to ease ED crowding and testing now; extends European accelerated-protocol data with US RCT evidence.
Does a 0/1-hour hs-cTnI accelerated protocol reduce health care resource utilization compared with a traditional 0/3-hour standard care protocol in ED patients with suspected MI?
Implementation of a 0/1-hour hs-cTnI protocol safely reduces ED length of stay and downstream cardiac testing compared to a standard 0/3-hour protocol in patients with suspected MI.
Miller et al. (2025) studied this question.
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