Why the study?
Cardiac complications from mediastinal radiotherapy are increasingly prevalent and represent a significant cause of morbidity and mortality following treatment.
Intracardiac radiation therapy can lead to significant conduction system disease such as Mobitz type II AV block requiring permanent pacing.
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May prompt closer ECG follow-up after targeted intracardiac radiation; leaves open incidence and should not yet change practice.
Cardiac complications from mediastinal radiotherapy are much more prevalent than in years past and are becoming a significant cause of morbidity and mortality in these patients following treatment. We describe a patient with metastatic lung adenosquamous carcinoma extending to the right ventricular outflow tract who would develop a Mobitz type II atrioventricular block following intracardiac radiation therapy requiring permanent pacemaker placement.
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Troxel et al. (2023) studied this question.
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