Why the study?
Does mechanical unloading alter troponin subunit isoform expression in rat soleus muscle?
Population
Rat soleus muscle
Design
Preclinical
Follow-up
Up to 28 days
Authors
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Rat unloading data should not change clinical practice; leaves open whether troponin isoform transitions occur in human muscle under disuse.
Does mechanical unloading alter troponin subunit isoform expression in rat soleus muscle?
Mechanical unloading of rat soleus muscle induces independent slow-to-fast isoform transitions of troponin subunits, particularly TnT.
Bastide et al. (2002) studied this question.
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