Serum Glutamic-Oxalacetic Transaminase Activity in Conditions Associated With Myocardial Infarction. I. Bodily Trauma

Article1 March 1957SERUM GLUTAMIC-OXALACETIC TRANSAMINASE ACTIVITY IN CONDITIONS ASSOCIATED WITH MYOCARDIAL INFARCTION. I. BODILY TRAUMAJACK LIEBERMAN, M.D., IRVING I. LASKY, M.D., S. I. DULKIN, Ph.D., OTTO E. LOBSTEIN, Ph.D.JACK LIEBERMAN, M.D., IRVING I. LASKY, M.D., S. I. DULKIN, Ph.D., OTTO E. LOBSTEIN, Ph.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-46-3-485 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSerum glutamic-oxalacetic transaminase (SGO-T) activity was originally demonstrated by LaDue, Wroblewski and Karmen in 1954 to be an aid in establishing the diagnosis of myocardial infarction.1This observation has since been confirmed by a number of other investigators.2-10Many of these same investigators have also demonstrated the value of the serum transaminase test as an index of liver cell injury.8-14In this regard the test has even been shown to be of value epidemiologically in revealing preclinical hepatitis or chronic lingering infection where other liver function studies are not significantly affected.14Active rheumatic carditis was also found to produce high...Bibliography1. 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GoldsteinIsraelSeligson FHLD: Use of serum transaminase levels in the differentiation of pulmonary embolism and myocardial infarction, New England J. Med. 254: 746-749, 1956. CrossrefMedlineGoogle Scholar17. AwaparaSeale JB: Distribution of transaminase in rat organs, J. Biol. Chem. 194: 497-502, 1952. CrossrefMedlineGoogle Scholar18. Lajoie RJ: Industrial trauma and heart disease, Indust. Med. and Surg. 22: 514-519, 1953. MedlineGoogle Scholar19. Lowry T: Question of cardiac trauma, Minn. Med. 34: 1016-1020 (Oct.) 1951. Google Scholar20. McGill RJ: Cardiac contusion; differentiation from infarction, Lancet 1: 997-998, 1952. CrossrefMedlineGoogle Scholar21. WachelTeich FWEM: Tall precordial T waves as the earliest sign in diaphragmatic wall infarction, Am. Heart J. 51: 91-97, 1956. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Torrance, California*Received for publication October 12, 1956.From the Department of Medicine, Harbor General Hospital, and the School of Medicine, University of California, Los Angeles.Aided by a research grant from the Attending Staff Association, Harbor General Hospital, Torrance, California.Requests for reprints should be addressed to Jack Lieberman, M.D., Harbor General Hospital, 1124 West Carson Street, Torrance, California. 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LOBSTEIN, Ph.D. 1 March 1957Volume 46, Issue 3Page: 485-496KeywordsAminotransferasesElectrocardiographyEpidemiologyHepatitis AHospital medicineLiverMyocardial infarctionMyocarditisNeutrophilsResearch grants ePublished: 1 December 2008 Issue Published: 1 March 1957 PDF downloadLoading ...