Brain Natriuretic Peptides as Biomarkers for Atherosclerosis
Why the study?
Can brain natriuretic peptide (BNP) and its amino-terminal fragment enhance risk stratification for coronary heart disease?
Population
Individuals at risk of coronary heart disease (CHD)
Design
Review
Authors
Discussion
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Member takes
Implication
BNP/NT-proBNP merit prospective validation for CHD risk stratification; leaves open incremental value over traditional factors.
Structured PICO
Can brain natriuretic peptide (BNP) and its amino-terminal fragment enhance risk stratification for coronary heart disease?
P
Population
Individuals at risk of coronary heart disease (CHD)
I
Intervention
Brain natriuretic peptide (BNP) and its amino-terminal fragment as biomarkers
O
Outcome
Prediction of coronary heart disease (CHD) risksurrogate
BNP and NT-proBNP are being explored as novel biomarkers to improve risk stratification for coronary heart disease beyond traditional risk factors.
Cite This Study
Ashley et al. (2008) studied this question.