Why the study?
BNP is used as a prognostic biomarker in ACS, prompting evaluation of serum NT-pro-BNP levels and their association with echocardiographic parameters and age in patients with ACS.
Does age affect serum NT-proBNP levels and echocardiographic parameters in patients with acute coronary syndrome?
Does age affect serum NT-proBNP levels and echocardiographic parameters in patients with acute coronary syndrome?
In patients with acute coronary syndrome, NT-proBNP is significantly elevated compared to controls, and increasing age is associated with changes in diastolic echocardiographic parameters (E/e and IVRT) but not significantly with NT-proBNP levels.
NT-proBNP elevation in ACS appears age-independent; hypothesis-generating for age effects on diastolic parameters in this population.
Background: B-type natriuretic peptide has been used as a biological marker for prognosis in patients with acute coronary syndrome (ACS). Acute Coronary Syndrome is one of the commonly diagnosed life threatening condition as of now. Aim: To estimate the serum level of N-terminal pro-Brain natriuretic peptide levels in Acute coronary syndrome. Also to find the association of serum NT-pro-BNP levels and echocardiographic parameter in ACS patients with age. Materials and Methods: 70 patients of age group between 25 to 84 of both sexes who got admitted within 24 hours after onset of symptoms and diagnosed as Acute Coronary at Baghdad Hospital medical city during the period of November 2020 to August 2021). The study patients were divided into four quartiles ages. The levels of NT-Pro BNP was measure in the blood with NT-Pro BNP Elisa Assay kit. Results: This study included 70 patients with means of age was (59.77±11.45) years the control group included 20 healthy persons with mean age (34.47±12.58) years and ranged from (20-58) years. Patients mean age was significantly higher than control group mean age (P-value =0.0149).
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Wafa M. Merza (2022) studied this question.
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