Why the study?
With reports of post-vaccine myocarditis/pericarditis in adolescents and upcoming COVID-19 vaccination, baseline pediatric epidemiology and clinical course prior to vaccine introduction were needed.
Before the introduction of COVID-19 vaccines, pediatric myocarditis/pericarditis in Korea occurred most frequently in male adolescents with favorable outcomes, while infants under 1 year faced the highest risk of poor clinical outcomes.
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Provides pre-vaccine Korean pediatric baseline as adolescent vaccination starts; leaves open post-vax incidence and severity comparisons.
BACKGROUND: Korean health authority plans to vaccinate adolescents against coronavirus disease 2019 (COVID-19) starting high school seniors during the summer vacation of 2021. However, the myocarditis/pericarditis following COVID-19 vaccine has been reported recently in adolescents and young adults. This study was performed to answer the urgent questions about the basic epidemiology and clinical course of myocarditis/pericarditis in hospitalized patients prior to the introduction of COVID-19 vaccines in pediatric population. METHODS: A retrospective medical record analysis including frequency, clinical characteristics, etiology and outcome of myocarditis/pericarditis was conducted in 17 years and younger patients who were hospitalized in two referral hospitals in Korea between 2010 and 2019. CONCLUSION: The frequency of myocarditis/pericarditis was highest among male adolescent in-patients; however, the outcome was favorable in this group without any mortality.
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Park et al. (2021) studied this question.
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