Why the study?
Little is known about the impact of marital or partner status on patient-reported outcome measures following acute myocardial infarction and stroke, despite its known association with lower morbidity and mortality.
Does married or partnered status improve patient-reported outcome measures in individuals aged 18 years and older diagnosed with an AMI or stroke?
Does married or partnered status improve patient-reported outcome measures in individuals aged 18 years and older diagnosed with an AMI or stroke?
This protocol outlines a systematic review to evaluate the association between marital/partner status and patient-reported outcome measures following acute myocardial infarction or stroke, including potential sex differences.
Does not change post-AMI/stroke care; will synthesize evidence on marital status, PROMs, and sex differences once completed.
Introduction Marital/Partner support is associated with lower mortality and morbidity following acute myocardial infarction (AMI) and stroke. Despite an increasing focus on the effect of patient-centered factors on health outcomes, little is known about the impact of marital/partner status on patient-reported outcome measures (PROMs). Objective To synthesize evidence of the association between marital/partner status and PROMs after AMI and stroke and to determine whether associations differ by sex. Methods and analysis We will search MEDLINE (via Ovid), Web of Science Core Collection (as licensed by Yale University), Scopus, EMBASE (via Ovid), and PsycINFO (via Ovid) from inception to January 10, 2022. Two authors will independently screen titles, abstracts, and then full texts as appropriate, extract data, and assess risk of bias. Conflicts will be resolved by discussion with a third reviewer. The primary outcomes will be the associations between marital/partner status and PROMs. Meta-analysis will be conducted if appropriate. Subgroup analysis by sex and meta-regression with a covariate for the proportion of male participants will be performed to explore differences by sex. Ethics and dissemination This research is exempt from ethics approval because the study will be conducted using published data. We will disseminate the results of the analysis in a related peer-reviewed journal. PROSPERO registration number CRD42022295975
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Zhu et al. (2022) studied this question.
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