October 1, 2005Lupus

Acute lupus myocarditis: clinical features and outcome of an oriental case series

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Structured PICO

Population

11 female patients with systemic lupus erythematosus (SLE) without atherosclerotic risk factors presenting with acute lupus myocarditis (ALM), mean age 27 +/- 10 years at SLE diagnosis, 46% Chinese.

Intervention

High dose corticosteroids (100% of patients) and intravenous pulse cyclophosphamide (64% of patients)

Outcome

Cardiac outcomes including survival, recurrence of ALM, and left ventricular ejection fraction (LVEF) recoveryhard clinical

Early immunosuppressive therapy with high-dose corticosteroids and pulse intravenous cyclophosphamide is associated with good cardiac recovery and survival in patients with acute lupus myocarditis.

Discussion

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Implication

May support early immunosuppression in acute lupus myocarditis; hypothesis-generating case series requiring prospective validation.

Cite This Study

Law et al. (2005) studied this question.

synapsesocial.com/papers/6a7feae933a54265d53d2dc6 https://doi.org/10.1191/0961203305lu2228oa

Topics

Echocardiography Myocarditis

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Acute lupus myocarditis: clinical features and outcome of an oriental case series

Structured PICO

Discussion

Implication

Cite This Study

Topics

Acute lupus myocarditis: clinical features and outcome of an oriental case series

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Topics

Also Consider