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The multipoint hydrogen-bonded complex 1 (R=alkanoyl) is readily formed between a ferrocene-modified artificial receptor and a dinucleotide. This principle can be used effectively in highly selective, large-scale separations of dinucleotides from mixtures of mono- and oligonucleotides. The process is economically viable and environmentally friendly.
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Inoûye et al. (2001) studied this question.
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