Why the study?
The direction of time is often ignored in biological signals, and the variation regularity of time irreversibility of heart rate variability during the initial stage of hypoxic exposure was unknown.
Does acute normobaric hypoxic exposure alter the time irreversibility of heart rate variability in healthy young men?
Population
Six young subjects without plateau or hypoxia experiences plus six MIT-BIH normal sinus rhythm database controls
Comparison
2 h acute normobaric hypoxic exposure at 12.9% oxygen concentration vs normal sinus rhythm database controls
Design
Experimental physiological study with database control group
Follow-up
2 h
Authors
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Acute hypoxia may impair autonomic HRV regulation in healthy men; leaves open clinical relevance and generalizability beyond this setting.
Does acute normobaric hypoxic exposure alter the time irreversibility of heart rate variability in healthy young men?
Acute hypoxic exposure leads to a sustained decline in time irreversibility of heart rate variability at short delay times, indicating weakened cardiovascular autonomic nervous system regulation.
Li et al. (2021) studied this question.
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