Why the study?
Leiomyosarcoma of the inferior vena cava is rare, prompting a review of patient manifestations, treatments, and outcomes.
In patients with rare inferior vena cava leiomyosarcoma, complete R0 surgical resection with appropriate venous management provides a chance for long-term survival with low perioperative mortality.
Individualized IVC reconstruction after R0 resection may be feasible; leaves open multicenter data on reconstruction and survival in this rare tumor.
OBJECTIVES: Leiomyosarcoma of the inferior vena cava (IVC) is rare. The study reviewed patients with IVC leiomyosarcoma in our hospital in the past ten years. METHODS: Twenty patients diagnosed with IVC leiomyosarcoma between October 2010 and October 2020 were enrolled. Their clinical manifestations, treatments, and follow-up results were analyzed. RESULTS: The sarcoma was located in the lower IVC segment in six patients, with 13 in the middle and one in the upper IVC segment. Eighteen patients underwent R0 resection. After resection, 16 patients (80%) had primary repair of the IVC, while four patients underwent ligation. During a mean follow-up of 37.7 months, seven patients died due to tumor metastasis, four patients were alive with the tumor recurrence and other nine patients were alive without recurrence. CONCLUSION: The management of the IVC after tumor resection depended on the tumor location and size. R0 resection provided a chance for long term survival.
No takes yet. Share an insight, caveat, or question.
Pan et al. (2022) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: