Why the study?
SARS-CoV-2 infection frequently has acute cardiovascular manifestations, but long-term sequelae remained to be described.
Does past SARS-CoV-2 infection cause long-term echocardiographic abnormalities in patients six months post-infection?
Does past SARS-CoV-2 infection cause long-term echocardiographic abnormalities in patients six months post-infection?
Six months after SARS-CoV-2 infection, patients showed globally preserved left and right ventricular systolic function on echocardiography, regardless of initial disease severity.
Routine 6-month echo is unlikely to explain post-COVID symptoms or change care; leaves open occult injury on CMR or later-wave cohorts.
INTRODUCTION AND OBJECTIVES: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection has frequent acute cardiovascular manifestations, but long-term sequelae are yet to be described. Our main objective is to describe the echocardiographic findings of patients with a previous SARS-CoV-2 infection. METHODS: A single-center prospective study was conducted. Patients who tested positive for SARS-CoV-2 were selected and submitted to a transthoracic echocardiogram six months after infection. A complete echocardiographic assessment was performed, including tissue Doppler, E/E' ratio, and ventricular longitudinal strain. Patients were divided into two subgroups according to their need for admission to the ICU. RESULTS: A total of 88 patients were enrolled. The mean values and respective standard deviations of the echocardiographic parameters were as follows: left ventricular ejection fraction 60.8 ± 5.9%; left ventricular longitudinal strain 17.9 ± 3.6%; tricuspid annular plane systolic excursion 22.1 ± 3.6 mm; a longitudinal strain of the free wall of the right ventricle 19.0 ± 6.0%. We found no statistically significant differences between subgroups. CONCLUSIONS: At the six-month follow-up, we found no significant impact of past SARS-CoV-2 infection on the heart using echocardiography parameters.
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Flores et al. (2023) studied this question.
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