Myasthenia Gravis Associated with Adrenocortical Insufficiency

SINCE 1901, when Laquer and Weigert1 first demonstrated a tumor of the thymus in a patient with myasthenia gravis, there have been many attempts to establish an endocrine basis for the myasthnic syndrome. In a comprehensive review published in 1943, McEachern2 summarizes with the statement that "myasthenia gravis does not appear to be connected with endocrine dysfunction except during pregnancy or in relation to the menses or to thyroid activity." After evaluation of the available clinical and experimental data, he could find no conclusive proof of an endocrine function for the thymus, but suggested that the gland might produce a . . .