A Mutation in the Thyroid Hormone Receptor Alpha Gene

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Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1A targeted dominant negative mutation of the thyroid hormone α1 receptor causes increased mortality, infertility, and dwarfism in mice2001 · 195 citations
2. 2The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all‐trans retinoic acid in patients with acute myeloid leukemia2005 · 226 citations
3. 3Thyroid Hormone Receptor α and Regulation of Type 3 Deiodinase2011 · 71 citations
4. 4A Point Mutation in the Activation Function 2 Domain of Thyroid Hormone Receptor α1 Expressed after CRE-Mediated Recombination Partially Recapitulates Hypothyroidism2007 · 105 citations