Why the study?
Determining endotypes of INOCA via invasive diagnostic tests plays an important role in prescribing optimal drug therapy that improves quality of life in patients without severe hemodynamically significant coronary stenosis.
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Population
Patients with angina and intact coronary arteries (INOCA)
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Should not yet change INOCA workup; leaves open prospective validation of this invasive endotyping algorithm.
This article presents modern views on the pathophysiological mechanisms of angina symptoms in patients without severe hemodynamically significant stenosis in the coronary arteries. An algorithm of invasive diagnostic tests is presented, which help to determine the endotypes of INOCA, which further plays an important role in order to prescribe optimal drug therapy that improves quality of life in this category of patients.
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Skybchyk et al. (2021) studied this question.
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