Why the study?
Does benidipine improve augmentation index and proteinuria compared to amlodipine in non-diabetic hypertensive patients with chronic kidney disease?
Does benidipine improve augmentation index and proteinuria compared to amlodipine in non-diabetic hypertensive patients with chronic kidney disease?
Benidipine may offer superior renoprotection and preservation of arterial compliance compared to amlodipine in non-diabetic CKD patients.
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Hypothesis-generating for differential CCB effects in non-diabetic CKD; should not change practice without randomized confirmation.
Takenaka et al. (2009) studied this question.
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