Why the study?
Does continuing versus stopping pre-existing antihypertensive therapy reduce death or dependency at 14 days in patients with acute stroke?
Population
2900 patients with suspected acute ischaemic and haemorrhagic stroke on pre-existing antihypertensive…
Comparison
Continue current antihypertensive therapy for… vs Stop current antihypertensive therapy for the…
Design
RCT, randomized, open, blinded-endpoint
Follow-up
6 months
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The COSSACS trial is designed to evaluate whether continuing or stopping pre-existing antihypertensive therapy in the acute phase of stroke improves clinical outcomes.
Does continuing versus stopping pre-existing antihypertensive therapy reduce death or dependency at 14 days in patients with acute stroke?
The COSSACS trial is designed to evaluate whether continuing or stopping pre-existing antihypertensive therapy in the acute phase of stroke improves clinical outcomes.
A 2005 study studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: