S ince its emergence in China late 2019, coronavirus disease (COVID-19) had caused >41 million cases and >1.1 million deaths globally by October 2020, according to the World Health Organization (https://www.who. int/publications/m/item/weekly-operational-update---30-october-2020). Diagnosis of the causative pathogen, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is based on reverse transcription-PCR (RT-PCR) to detect viral nucleic acid or serologic assays to detect SARS-CoV-2 antigens in early stages of disease (1,2). In later stages of disease, antibody-based serologic testing can complement diagnosis of SARS-CoV-2 |infection.
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Yadouléton et al. (2020) studied this question.