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March 12, 2025BMC Public Health25 citationsOpen Access

Global, regional, and national epidemiology of ischemic heart disease among individuals aged 55 and above from 1990 to 2021: a cross-sectional study

Population

Individuals aged 55 and above diagnosed with ischemic heart disease between 1990 and 2021 across 204…

Design

Cross-sectional

Follow-up

1990 to 2021

Authors

PXPeng XueLLLing LinPLPeishan Li

Discussion

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Overview

Rising absolute IHD cases in lower-SDI older adults caution against complacency from falling rates; leaves open whether SBP-diet-LDL-pollution control can close disparities.

Structured PICO

P
Population
Individuals aged 55 and above diagnosed with ischemic heart disease (IHD) between 1990 and 2021 across 204 countries and regions.
O
Outcome
Trends in IHD incidence, all cause and cause-specific deaths, disability-adjusted life years (DALYs), and corresponding estimated annual percentage changes (EAPCs) from 1990 to 2021hard clinical

Despite declining global rates of IHD incidence and mortality, the absolute burden of disease is increasing, particularly in low- and middle-SDI regions, driven by population aging and risk factors like high systolic blood pressure.

Limitations

  • potential underrepresentation of data in low-income regions
  • reliance on modeling in middle and low SDI regions
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Cite This Study

Xue et al. (2025) studied this question.

synapsesocial.com/papers/6a8012f801fdebfcdaee9f66https://doi.org/10.1186/s12889-025-22193-6
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