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August 15, 2026Journal of Clinical MedicineOpen Access

Factors Associated with 30- and 90-Day Mortality After Percutaneous Cholecystostomy for Acute Cholecystitis: A Single-Centre Retrospective Cohort Study

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Authors

BABerkan AcarAMAli MuhtaroğluEYEsengul Yılmaz

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Overview

Retrospective cohort study reveals Tokyo grade III disease and ICU admission drive early mortality in acute cholecystitis treated with percutaneous cholecystostomy, highlighting high-risk profiles.

Key Points

  • To identify clinical factors and patient characteristics associated with 30- and 90-day mortality following percutaneous cholecystostomy for acute cholecystitis.
  • Analyzed a single-centre retrospective cohort of 84 consecutive patients treated between December 2021 and December 2025.
  • Evaluated clinical features, comorbidity, Tokyo severity grade, ICU admission, microbiology, and laboratory values using separate age-adjusted logistic regression models.
  • Thirty-day mortality was 14.3% (12/84; 95% CI, 8.4–23.3), and 90-day mortality was 24.4% (20/82; 95% CI, 16.4–34.7).
  • ICU admission during the index episode was associated with increased 30-day mortality (OR, 14.31; 95% CI, 2.77–73.99) and 90-day mortality (OR, 21.10; 95% CI, 5.65–78.85) in age-adjusted models.
  • Tokyo grade III disease was also strongly associated with higher 30-day mortality (OR, 9.44; 95% CI, 1.84–48.35) and 90-day mortality (OR, 19.07; 95% CI, 4.74–76.66).

Cite This Study

Acar et al. (2026) studied this question.

synapsesocial.com/papers/6a8019db75c2e31742c8608ehttps://doi.org/10.3390/jcm15166270
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Early predictors of in-hospital mortality after percutaneous cholecystostomy2026
  2. 2Prognostic Factors and Predictive Models for Rates of Mortality and Morbidity Following Percutaneous Cholecystostomy: A Retrospective Cohort Study at Counties Manukau Between 2022 and 20242026
  3. 3Clinical outcomes of percutaneous cholecystostomy in patients with acute cholecystitis classified according to the Tokyo guidelines, 2018: A single-center, retrospective, observational study.2026
  4. 4Percutaneous cholecystostomy in acute complicated versus uncomplicated cholecystitis; is there a difference in outcomes? A single-center experience2024
  5. 5Factors Affecting Cholecystostomy Tube Removal and Interval Cholecystectomy Timing After Percutaneous Cholecystostomy for Acute Cholecystitis2026