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Clinical review outlines the pathophysiology and treatment of Clostridium perfringens infections, highlighting interprofessional strategies for managing foodborne illness.
The anaerobic Gram-positive spore-forming bacillus Clostridium perfringens is linked to acute gastrointestinal infections in people that range in severity from diarrhea to necrotizing enterocolitis and myonecrosis. This pathogen can produce spores that are resistant to environmental stress and has an arsenal of poisons necessary for disease development. Spores of C. perfringens may withstand typical cooking temperatures. Therefore, it can expand in foods that are improperly stored. Outbreaks are most commonly related to improperly heated or reheated gravy, poultry, or meats. The epidemiology, pathophysiology, and other important aspects relevant to the interprofessional team's treatment of patients with Clostridium perfringens infections will be explained in this activity.
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E. et al. (2026) studied this question.
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