What question did this study set out to answer?

To identify and compare the clinical, anamnestic, and reproductive characteristics of infertile women with and without autoimmune thyroiditis.

August 15, 2026Journal of modern medicineOpen Access

Clinical, Anamnestic and Reproductive Characteristics of Women With Infertility Associated With Autoimmune Thyroiditis

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Authors

RSR.B. Soliyeva SZSh.A. Zufarova

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Implication

Comparative observational study reveals higher rates of combined-factor infertility in women with autoimmune thyroiditis, indicating thyroid autoimmunity acts as a reproductive disease modifier.

Key Points

To identify and compare the clinical, anamnestic, and reproductive characteristics of infertile women with and without autoimmune thyroiditis.
Comparative observational study involving 190 infertile women aged 20–44 years, comparing a cohort with verified autoimmune thyroiditis (n=100) against a control group without thyroid autoimmunity (n=90).
Evaluated age, infertility duration and classification, obstetric history, gynaecological comorbidities, previous surgeries, and hysterosalpingography findings using odds ratios and multivariable logistic regression.
Patients with autoimmune thyroiditis were older (32.09±5.31 vs 29.92±5.03 years; p=0.004) and experienced a longer duration of infertility (8.44±4.55 vs 7.11±4.01 years; p=0.034).
Combined-factor infertility was significantly elevated in the autoimmune group (34.0% vs 13.3%; OR=3.35, 95% CI 1.61–6.98; p=0.001), whereas isolated tubal-factor infertility was lower (18.0% vs 44.4%; OR=0.27, 95% CI 0.14–0.53; p<0.001).
Uterine fibroids, breast disorders, and prior diagnostic hysteroscopy were significantly more prevalent among women with autoimmune thyroiditis, while endometrial polyp rates showed no significant difference.

Cite This Study

Soliyeva et al. (2026) studied this question.

synapsesocial.com/papers/6a801a3a75c2e31742c86cb2 https://doi.org/10.67519/nshr.ztj.2026.03.105

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Implication

Comparative observational study reveals higher rates of combined-factor infertility in women with autoimmune thyroiditis, indicating thyroid autoimmunity acts as a reproductive disease modifier.

Clinical, Anamnestic and Reproductive Characteristics of Women With Infertility Associated With Autoimmune Thyroiditis

Discussion

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Implication

Key Points

Cite This Study

Clinical, Anamnestic and Reproductive Characteristics of Women With Infertility Associated With Autoimmune Thyroiditis

Discussion

Member takes

Implication

Key Points

Cite This Study

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