Why the study?
Are lymphopenia, eosinopenia, and elevated cortisol levels more common in patients admitted with heart failure compared to other admissions?
Are lymphopenia, eosinopenia, and elevated cortisol levels more common in patients admitted with heart failure compared to other admissions?
Lymphopenia and eosinopenia observed in acute heart failure admissions are likely part of a physiological stress response, as evidenced by elevated cortisol levels.
Lymphopenia and eosinopenia may reflect stress response in acute HF; leaves open diagnostic utility beyond cortisol and requires prospective validation.
The incidence of lymphopenia and eosinopenia in 10 patients admitted to hospital in heart failure was compared with that in 11 ;cold' admissions and 10 with acute diseases admitted via the Casualty Department. Plasma cortisol determinations were made simultaneously. A significant difference was found between the heart failure group and the ;cold' controls in respect of lymphopenia, eosinopenia, and cortisol levels. The ;acute' control patients showed an overlap with both groups. It is concluded that this lymphopenia is part of a response to stress.Seventy-two hours after admission there was no significant change in these values although the figures suggest the beginning of a return to normal.
No takes yet. Share an insight, caveat, or question.
Hurdle et al. (1966) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: