Population
809 subjects with high normal blood pressure (mean 134+/-4/85+/-4 mm Hg), mean age 49+/-8.1 years.
Comparison
Low-dose angiotensin receptor blocker for 2 years vs Placebo (main trial comparator)
Design
Cross-sectional, randomized (main trial), placebo-controlled (main trial)
Authors
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May warrant broader risk evaluation in high normal BP; leaves open whether isolated cases merit intervention.
Individuals with high normal blood pressure frequently have multiple additional cardiovascular risk factors, suggesting that truly low-risk hypertension rarely exists.
Nesbitt et al. (2005) studied this question.
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