January 1, 1999AJP Regulatory Integrative and Comparative Physiology
Potassium fluxes in contracting human skeletal muscle and red blood cells
Population
7 subjects
Comparison
Two-legged submaximal knee-extensor exercise for… vs Leg exercise alone (L1)
Design
Other
Follow-up
30 minutes
Authors
Discussion
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Member takes
Implication
Muscle K+ uptake during intense exercise may limit hyperkalemia; leaves open clinical relevance for arrhythmia risk or exercise testing.
Structured PICO
P
Population
7 subjects
I
Intervention
Two-legged submaximal knee-extensor exercise for 30 min with intense arm exercise added for 10 min (L2+A)
C
Comparator
Leg exercise alone (L1)
O
Outcome
K+ fluxes in red blood cells and musclesurrogate
Contracting muscle can take up K+ during intense exercise, likely via hormone and K+ activation of the Na+-K+ pump, while red blood cell K+ changes are due to water movements.
Cite This Study
Juel et al. (1999) studied this question.