Studies on the Chronic Toxicity of Chloroquine (Sn-7618) 1

C h lo ro q u i ne, 7-chloro-4-(4-diethylamino-l- methylbutylamino) quinoline, is an antimalarial drug of the 4-amino quinoline series. It has been shown to have antimalarial activity similar to and superior to that of quinacrine in avian malaria, and in trophozoiteand sporozoite-induced vivax and falciparum malaria in man ( 1, 2, 3, 4).