Why the study?
Surgical site infections represent a major source of healthcare-associated infections, while extensive indiscriminate antibiotic use has led to the development of resistance.
Does a single stat dose of first generation cephalosporin 1gm IV prevent postoperative wound infection in patients undergoing elective clean surgeries?
Does a single stat dose of first generation cephalosporin 1gm IV prevent postoperative wound infection in patients undergoing elective clean surgeries?
A single prophylactic dose of 1g IV first-generation cephalosporin in clean elective surgeries is associated with a low postoperative infection rate of 3%.
May support single-dose cephalosporin prophylaxis in clean elective surgery; leaves open need for randomized confirmation.
Background: Health care associated infections (HAIs) present a significant source of preventable morbidity and mortality. More than 30% of all HAIS are represented by surgical site infections (SSIs) making them most common sub types between 1.9% and 2.7% of all surgical patients. Joseph Lister “the man who made surgery safe” introduced antiseptic method for safe surgeries. As many are now considering antibiotics “wonder drug” which covers the surgical techniques and having asepsis. Extensive indiscriminate use of antibiotics has resulted in developing resistance.Methods: Study conducted in about 100 cases in various surgical units having various surgical procedures. Only clean cases are taken. A single stat dose of first generation cephalosporin 1gm given IV at the time of giving anesthesia. Postoperative any signs and symptoms like infections, fever with chills, wound discharge are observed. If any evidence of wound infection is present, accordingly sent for culture and sensitivity and suitable antibiotics are given.Results: In our study 5 patients had fever with serous discharge 2 patients showed no growth, 3 patients had got growth positive (2- staphylococcus aurous, 1- pseudomonas). Hence our infection rate is 3%.Conclusions: Single dose prophylaxis has got definite advantage to overcome the postoperative wound sepsis. Prolonged antibiotic therapy should be avoided as it has got no added advantaged over single dose antibiotic.
No takes yet. Share an insight, caveat, or question.
Ali et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: