Key result
CAD management in patients ≥80 years requires patient-centered care weighing frailty and cognitive skills.
Why the study?
Coronary artery disease is a major cause of morbidity and mortality in patients ≥80 years of age, but older patients have typically been under-represented in cardiovascular clinical trials.
Systematic Review
Highlights the need for a patient-centered approach, accounting for frailty and cognitive skills, when managing coronary artery disease in patients aged 80 and older.
Supports frailty-informed CAD decisions now; leaves open dedicated RCTs given systematic underrepresentation of adults ≥80.
Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients ≥80 years of age. Nonetheless, older patients have typically been under-represented in cardiovascular clinical trials. Understanding the pathophysiology, epidemiology, and optimal means of diagnosis and treatment of CAD in older adults is crucial to improving outcomes in this high-risk population. A patient-centered approach, taking into account health status, functional ability and frailty, cognitive skills, and patient preferences is essential when caring for older adults with CAD. The present systematic review focuses on the current knowledge base, gaps in understanding, and directions for future investigation pertaining to CAD in patients ≥80 years of age.
No takes yet. Share an insight, caveat, or question.
Madhavan et al. (2018) conducted a systematic review in Coronary artery disease. A systematic review of coronary artery disease in patients ≥80 years of age emphasizes the need for a patient-centered approach considering frailty, cognitive skills, and patient preferences.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: