What question did this study set out to answer?

To review updates from the past five years in therapeutic strategies for infantile hemangiomas, detailing efficacy, safety profiles, and treatment modalities.

May 26, 2022Frontiers in PharmacologyOpen Access

Update on Treatment of Infantile Hemangiomas: What’s New in the Last Five Years?

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Authors

LMLaura MaccaUniversity of Messina DADomenica AltavillaUniversity of Messina LBLuca Di BartolomeoÉcole Polytechnique Fédérale de Lausanne

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Implication

Literature review demonstrates effective lesion clearance in infants with hemangiomas, highlighting beta-blockers as safer alternatives to systemic steroids.

Key Points

To review updates from the past five years in therapeutic strategies for infantile hemangiomas, detailing efficacy, safety profiles, and treatment modalities.
Conducted a structured literature search across PubMed and EMBASE databases using search strings combining cutaneous infantile hemangioma and treatment.
Synthesized evidence covering labeled drugs, off-label topical and systemic therapies, pulsed dye laser, and syndromic manifestations including PHACE and LUMBAR syndromes.
Beta-blockers have largely replaced systemic steroids as the gold standard, with oral propranolol and topical options (timolol and carteolol) providing favorable safety and efficacy profiles.
Alternative off-label agents such as sirolimus and itraconazole, alongside pulsed dye laser therapy, offer targeted intervention strategies for complicated, refractory, or syndromic lesions.

Cite This Study

Macca et al. (2022) studied this question.

synapsesocial.com/papers/6a802fe9cf96de1eb9c86a80 https://doi.org/10.3389/fphar.2022.879602

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Implication

Literature review demonstrates effective lesion clearance in infants with hemangiomas, highlighting beta-blockers as safer alternatives to systemic steroids.

Update on Treatment of Infantile Hemangiomas: What’s New in the Last Five Years?

Discussion

Member takes

Implication

Key Points

Cite This Study

Update on Treatment of Infantile Hemangiomas: What’s New in the Last Five Years?

Discussion

Member takes

Implication

Key Points

Cite This Study

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