Review demonstrates advances in hardware and computing architectures mimicking biological neural circuits, highlighting pathways toward biohybrid intelligence and brain-machine interfaces.
Neuromorphic devices are bioinspired electronic systems that mimic key structures and functions of the nervous system, enabling integration and communication between living tissues and machines. This review examines how neuromorphic devices and computing are designed to emulate the structure, organization, and function of the nervous system. For neuromorphic devices, we first describe strategies that mimic subcellular neural functions. We then highlight how device architecture recapitulates biological topology from subcellular components to brain networks. We next summarize how neuromorphic devices emulate sensory and sensorimotor (sensory–modulation) neural circuits. For neuromorphic computing, we review recent advances in artificial and biological neuromorphic computing, including spiking neural networks, bioinspired learning algorithms, and applications. We also discuss emerging biohybrid intelligence systems leveraging two‐ and three‐dimensional biological networks as computational units. Finally, we outline key challenges, potential milestones, and future directions.
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Zhu et al. (2026) studied this question.
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