Why the study?
Retroperitoneal liposarcomas present vaguely with locoregional invasion that often requires customized surgical oncological measures such as en bloc resection.
This case highlights the need for customized surgical oncological measures, such as en bloc resection, in the treatment of solid abdominal tumours with locoregional invasion.
Answers are grounded in this paper and cite their sources.
May support MDT-guided radical resection of giant retroperitoneal liposarcoma despite organ invasion; leaves open generalizability from this single case.
Retroperitoneal liposarcomas are a heterogeneous group of mesenchymal tumours that have a wide spectrum of histological subtypes and vague clinical presentations. Herein, we present the case of a 75-year-old man with anorexia, weight loss of 7 kg, and a growing abdominal circumference within a span of 6 weeks. Computed tomography of the abdomen and pelvis showed a large mass that filled almost the entire abdominal cavity. After consultation with a multidisciplinary tumour board, en bloc resection of the tumour was performed. In addition, the left kidney and a part of the left diaphragm were removed. The tumour measured 35 × 29 × 20.5 cm and weighed 11.6 kg. The histological report confirmed low-grade dedifferentiated liposarcoma with scarce atypical adipocytes, lipoblasts containing spindle cell, pleomorphic, and chondroid components. The patient had uneventful recovery and remained stable during the follow-up period. We report this case to highlight the need for customized surgical oncological measures in the treatment of solid abdominal tumours due to locoregional invasion that usually necessitates en bloc resection.
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Herzberg et al. (2019) studied this question.
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