Key result
Open surgical resection of a 40 × 27 × 17 cm retroperitoneal liposarcoma resulted in an uneventful postoperative course, but the patient died of respiratory distress after 1 year of chemotherapy.
Case Report (n=1)
This case report highlights the surgical management of a giant retroperitoneal liposarcoma, demonstrating an uneventful postoperative course but ultimate mortality from respiratory distress after 1 year of chemotherapy.
Documents successful resection of advanced retroperitoneal liposarcoma; leaves open optimal multimodal strategies and long-term outcomes.
Liposarcoma is a rare malignant tumor of mesenchymal origin. It accounts for ~7% of all mesenchymal sarcomas and 1% of cancers in general. Its incidence does not exceed 2.5 cases per million inhabitants per year. This tumor is generally locally invasive, often diagnosed at an advanced stage, and can grow to a considerable size and weight, culminating in a locally advanced form. We report a case of a 65-year-old patient with retroperitoneal liposarcoma treated by open surgical resection. The patient was admitted for the management of an abdomino-pelvic mass measuring 40 × 27 × 17 cm, progressively evolving over 5 years. The diagnosis was established by computed tomography scan. The postoperative course was uneventful, and after 1 year of chemotherapy, the patient died of respiratory distress.
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Hassani et al. (2025) conducted a case report in giant retroperitoneal liposarcoma (n=1). open surgical resection was evaluated. Open surgical resection of a 40 × 27 × 17 cm retroperitoneal liposarcoma resulted in an uneventful postoperative course, but the patient died of respiratory distress after 1 year of chemotherapy.
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