Answers are grounded in this paper and cite their sources.
OTf: Ovotransferrin, OTf-cbp(n): Ovotransferrincarboplatin conjugate (drug: OTf mole ratio), OTf-PTX(n): Ovotransferrin-paclitaxel conjugate (drug:OTf mole ratio), TfR: Transferrin receptor Among common chemotherapies currently in use are [1] antimetabolites, work by interefering with metabolism of proliferating cells such as methotrexate and 5-fluorouracil; [2] alkylating agents, work by damaging DNA and result in death of growing cells such as cisplatin and carboplatin; and [3] mitosis inhibitors, work by targeting microtubules required in cell division such as taxol and paclitaxel. The
No takes yet. Share an insight, caveat, or question.
Ibrahim et al. (2020) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: