Pathogenetically based integrative therapeutic strategies in management of autism spectrum disorders

Autism and Autism spectrum disorders are the neurodevelopmental conditions characterized by persistent deficits in social communication and restricted repetitive behaviors.In spite of its occurrence being increasing from year to year, until now there is no unified opinion about etiology and pathogenesis of ASD.There is no widely accepted medical treatment for ASD as well.Authors summarized relevant data on the etiology of ASD, radiological findings in brain that persistent in autistic individuals, and proposed a pathogenetically based treatment protocol that implements a holistic integrative approach.The article summarizes therapeutic protocols proposed for complementary therapy of ASD that includes biomolecular therapies, immunotherapy, physiotherapy, speech therapy, nutrition and psychological support.