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January 2, 2013BMC PediatricsOpen Access

Persistent wandering atrial pacemaker after epinephrine overdosing – a case report

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Population

A previously healthy 3-year-old boy presenting with viral laryngotracheobronchitis.

Design

Case_report

Follow-up

18 months

Authors

EAElhadi H. AburawiUnited Arab Emirates UniversityHNHassib NarchıUnited Arab Emirates UniversityASAbdul‐Kader SouidUniversity of South Alabama

Discussion

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Implication

Epinephrine overdose in toddlers may cause persistent arrhythmia; this case leaves open incidence, reversibility, and prevention strategies.

Structured PICO

P
Population
A previously healthy 3-year-old boy (weight 17.5 kg, height 102.5 cm) presenting with viral laryngotracheobronchitis (croup).
I
Intervention
Iatrogenic overdose of epinephrine (1 mg administered by intravenous push, approximately 6-times the recommended dose).
O
Outcome
Development of arrhythmias (multifocal atrial tachycardia and wandering atrial pacemaker)safety

Iatrogenic intravenous epinephrine overdose in a toddler can cause acute multifocal atrial tachycardia and potentially persistent wandering atrial pacemaker.

Limitations

  • No ECG prior to the episode, so it cannot be definitively confirmed that the wandering atrial pacemaker did not exist before the epinephrine administration.

Cite This Study

Aburawi et al. (2013) studied this question.

synapsesocial.com/papers/6a804ca803a7c7d587cad83fhttps://doi.org/10.1186/1471-2431-13-1
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Potentiation by Thiopental of Halothane–Epinephrine-induced Arrhythmias in Dogs1982 · 26 citations
  2. 2Study of Cardiac Rate and Rhythm Patterns in Ambulatory and Hospitalized Children2005 · 39 citations
  3. 3Ectopic activity in the rat pulmonary vein can arise from simultaneous activation of α1‐ and β1‐adrenoceptors2007 · 39 citations
  4. 4Normal limits for heart rate as established using 24-hour ambulatory electrocardiography in children and adolescents2008 · 60 citations