Why the study?
Pregnancy-associated acute kidney injury continues to contribute to substantial maternal and fetal morbidity and mortality despite obstetric care advancements, posing ongoing diagnostic challenges.
Provides updated consensus recommendations on the diagnostic approaches and investigational tools for pregnancy-associated acute kidney injury.
Should now guide diagnostic workup of pregnancy-associated AKI; extends prior reviews into consensus while leaving prospective validation open.
Despite advancements in obstetric care, pregnancy-associated acute kidney injury (PrAKI) continues to be a significant public health concern, contributing to substantial maternal and fetal morbidity and mortality. The most common causes of PrAKI include preeclampsia/eclampsia, haemorrhage and infection. Diagnosis is influenced by gestational age and individual risk factors. Alongside traditional investigations such as imaging and kidney biopsy, novel diagnostics and biomarkers may provide valuable insights for differential diagnosis. This review aims to offer an update on the diagnostic approaches and investigational tools for PrAKI, while also addressing current challenges in the diagnostic paradigm and presenting recommendations for clinical practice and future research.
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Lumlertgul et al. (2025) conducted a review in Pregnancy-associated acute kidney injury (PrAKI). Diagnostic approaches and investigational tools was evaluated. This consensus review provides updated recommendations on diagnostic approaches, novel biomarkers, and investigational tools for managing pregnancy-associated acute kidney injury.
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