Population
Rat embryonic cortical neurons in primary culture and synthetic/zinc-reconstituted domain peptides of…
Comparison
Exposure to S-nitrosothiols vs Exposure to reactive oxygen species and…
Design
Preclinical
Authors
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MT-III may modulate NO-zinc signaling in neurons; leaves open relevance to human nitrosative stress disorders.
MT-III specifically converts NO signals to zinc signals via transnitrosation, which may be important for its role as a neuronal growth inhibitory factor and in brain diseases related to nitrosative stress.
Chen et al. (2002) studied this question.
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