A review to elucidate the role and scope of topical ozenoxacin in routine surgical practice in India

Superficial skin infections are a prevalent and are a significant challenge in surgical practice, particularly in India, where high surgical volumes and a high prevalence of comorbidities elevate the risk of infection. The use of topical antibiotics is a widely known strategy for preventing and managing superficial skin infections, yet the rise of antibiotic resistance demands innovative solutions. Based on the clinical evidence, epidemiology of superficial skin infections in surgical practice, risk factors, and panel discussion, this expert opinion aims to guide clinicians to optimize the use of ozenoxacin in surgical practice. The role of ozenoxacin, a novel fluoroquinolone, has been explored as an effective topical antibiotic for the treatment of superficial skin infection seen in surgical practice such as cellulitis, erysipelas, impetigo, ecthyma, folliculitis, furuncles, carbuncles, abscesses, and infections related to minor trauma. The article highlights ozenoxacin’ s mechanism of action, its broader antimicrobial coverage against gram-positive pathogens, and its potential advantages over older topical antibiotics.