Why the study?
Does concurrent administration of RRV with OPV, IPV, or DTP affect immunogenicity in 6-week-old infants?
Population
72 infants (6 weeks old) in Lahore, Pakistan
Comparison
Oral rhesus rotavirus vaccine given concurrently… vs Different vaccine combinations
Design
Cohort
Follow-up
up to 21 weeks
Authors
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RRV coadministration with OPV was associated with higher rotavirus seroresponse than DTP or IPV; leaves open optimal infant vaccine scheduling.
Does concurrent administration of RRV with OPV, IPV, or DTP affect immunogenicity in 6-week-old infants?
Concurrent administration of rhesus rotavirus vaccine with oral poliovirus vaccine does not interfere with the immune response to either vaccine in infants, though overall rotavirus seroconversion was low.
Jalil et al. (1991) studied this question.
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