Why the study?
Is the presence and severity of breast arterial calcification on mammograms associated with coronary artery calcification and stenosis on CTCA in females?
Is the presence and severity of breast arterial calcification on mammograms associated with coronary artery calcification and stenosis on CTCA in females?
In this small retrospective cohort, the severity of breast arterial calcification on mammography did not significantly correlate with coronary artery calcification scores on CTCA.
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Breast arterial calcification severity showed no correlation with coronary calcification in this cohort; leaves open its role in cardiovascular risk assessment and requires prospective validation.
Materials and Females included in the study were those who had Computed Tomography Coronary Angiography (CTCA) done within one year of mammography, which showed breast arterial calcification (BAC).Breast artery calcification (BAC) was classified into mild, moderate, or severe. The presence of coronary artery calcification(CAC) and the calcium score were determined for all females. With respect to coronary artery stenosis, patients were classified into three groups: normal (no stenosis), nonsignificant stenosis (less than 50% of luminal narrowing), or significant stenosis (equal to or more than 50% of luminal narrowing) (15). The correlation between BAC site and severity, CAC scoresand coronary artery stenosis was determined. The mean age of those females was 63.41 8.12 years.15% of the females with BAC and coronary artery calcification had unilateral BAC, while 85% of them had bilateral BAC, the correlation of which was statistically significant. There was also a significant difference between females with BAC and coronary artery calcification (59%) and those with BAC and no coronary artery calcification (41%). On the other hand, females with severe BAC and non-significant coronary artery stenosis were less than those with moderate BAC and coronary artery stenosis (25% and 37.5%, respectively). In addition, there was no significant correlation between the severity of BAC and CAC scores (r: 0.08, P: <0.05).
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Mohamed et al. (2016) studied this question.
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