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January 31, 2019HaematologicaOpen Access

Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study

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CRCarmelo RizzariIstituti di Ricovero e Cura a Carattere ScientificoCLClaudia Lanvers‐KaminskyUniversity Hospital MünsterMVMaria Grazia ValsecchiAzienda Ospedaliera San Gerardo

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Rizzari et al. (2019) studied this question.

synapsesocial.com/papers/6a809cad33a54265d53d535fhttps://doi.org/10.3324/haematol.2018.206433
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Serum asparaginase activities and asparagine concentrations in the cerebrospinal fluid after a single infusion of 2,500 IU/m2 PEG asparaginase in children with ALL treated according to protocol COALL-06-972005 · 42 citations
  2. 2Treating Childhood Acute Lymphoblastic Leukemia without Cranial Irradiation2009 · 1,236 citations
  3. 3L-asparaginase activity in plasma and other biological fluids1970 · 59 citations